Tunable Methacrylamides for Covalent Ligand Directed
Mar 25, 2021· Targeted covalent inhibitors are an important class of drugs and chemical probes. However, relatively few electrophiles meet the criteria for successful covalent inhibitor design. Here we describe α-substituted methacrylamides as a new class of electrophiles suitable for targeted covalent inhibitors. While typically α-substitutions inactivate acrylamides, we show
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Jan 09, 2020· Molecular imprinting strategy. Molecular imprinting (MI) is a chemical technique to create template-shaped cavities in polymer matrices with memory of the template molecules to be used for molecular recognition [8, 22,23,24,25,26,27,28].In contrast to the other approaches to molecular recognition discussed in this review, molecular imprinting depends on the use of
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Mar 09, 2021· Carbon dioxide (CO 2) is cheap, renewable, abundant, and nontoxic carbon feedstocks in chemical reactions.In the past two decades, utilization of CO 2 in polymer science has become a meaningful topic bridging two separate subjects, namely CO 2 valorization and sustainable polymer synthesis. This review summarizes the recent progress in CO 2
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N. Korea's parliamentary session. This photo, released by North Korea's official Korean Central News Agency on Sept. 30, 2021, shows Kim Yo-jong, North Korean leader Kim Jong-un's sister and currently vice department director of the ruling Workers' Party's Central Committee, who was elected as a member of the State Affairs Commission, the country's
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